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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PKN3 All Species: 7.88
Human Site: S306 Identified Species: 12.38
UniProt: Q6P5Z2 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6P5Z2 NP_037487.2 889 99421 S306 S P A A A L A S S P S E G W L
Chimpanzee Pan troglodytes XP_001159776 886 99121 S306 S P A A A L A S S P S E G W L
Rhesus Macaque Macaca mulatta XP_001110500 1011 111864 G419 S P A A A L A G S P S D G W L
Dog Lupus familis XP_548434 951 104664 G368 S P A A A L A G S P S Q G W L
Cat Felis silvestris
Mouse Mus musculus Q8K045 878 97863 G299 S P M A V L A G S P S E S W L
Rat Rattus norvegicus O08874 985 112050 L357 S K A T S V A L P G W S P S E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506565 993 109767 G406 S R V A T V L G S P G E S R P
Chicken Gallus gallus XP_422357 1013 114806 L382 S K A T S V T L P G W S P N E
Frog Xenopus laevis Q7ZX15 486 56292 K14 I K E G W L Q K R G E Y I K T
Zebra Danio Brachydanio rerio XP_697542 940 106140 S345 C R V S N M S S A P G S P S D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P13678 634 71138 H162 K R F T F C D H C G S L L Y G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34885 707 80133 K219 C H E D V V W K C P G N K A D
Sea Urchin Strong. purpuratus XP_787090 799 90414 N217 S T K E E I S N E I S A I M K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P24583 1151 131500 S294 A I M W L L L S D I A E E I R
Red Bread Mold Neurospora crassa P87253 1142 127954 A380 A Q S P Q F A A P P T S P G S
Conservation
Percent
Protein Identity: 100 97.7 81.5 84.2 N.A. 83.2 49.9 N.A. 64.2 48.9 26.2 52.2 N.A. 28 N.A. 29.1 41.5
Protein Similarity: 100 97.8 82.9 87.6 N.A. 88.4 63.6 N.A. 72.9 63 36.6 67.6 N.A. 41.5 N.A. 43.9 58.2
P-Site Identity: 100 100 86.6 86.6 N.A. 73.3 20 N.A. 33.3 13.3 6.6 13.3 N.A. 6.6 N.A. 6.6 13.3
P-Site Similarity: 100 100 93.3 93.3 N.A. 73.3 33.3 N.A. 40 26.6 6.6 40 N.A. 13.3 N.A. 13.3 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.2 27.1
Protein Similarity: N.A. N.A. N.A. N.A. 41.7 43.2
P-Site Identity: N.A. N.A. N.A. N.A. 20 13.3
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 40
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 14 0 40 40 27 0 47 7 7 0 7 7 0 7 0 % A
% Cys: 14 0 0 0 0 7 0 0 14 0 0 0 0 0 0 % C
% Asp: 0 0 0 7 0 0 7 0 7 0 0 7 0 0 14 % D
% Glu: 0 0 14 7 7 0 0 0 7 0 7 34 7 0 14 % E
% Phe: 0 0 7 0 7 7 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 7 0 0 0 27 0 27 20 0 27 7 7 % G
% His: 0 7 0 0 0 0 0 7 0 0 0 0 0 0 0 % H
% Ile: 7 7 0 0 0 7 0 0 0 14 0 0 14 7 0 % I
% Lys: 7 20 7 0 0 0 0 14 0 0 0 0 7 7 7 % K
% Leu: 0 0 0 0 7 47 14 14 0 0 0 7 7 0 34 % L
% Met: 0 0 14 0 0 7 0 0 0 0 0 0 0 7 0 % M
% Asn: 0 0 0 0 7 0 0 7 0 0 0 7 0 7 0 % N
% Pro: 0 34 0 7 0 0 0 0 20 60 0 0 27 0 7 % P
% Gln: 0 7 0 0 7 0 7 0 0 0 0 7 0 0 0 % Q
% Arg: 0 20 0 0 0 0 0 0 7 0 0 0 0 7 7 % R
% Ser: 60 0 7 7 14 0 14 27 40 0 47 27 14 14 7 % S
% Thr: 0 7 0 20 7 0 7 0 0 0 7 0 0 0 7 % T
% Val: 0 0 14 0 14 27 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 7 7 0 7 0 0 0 14 0 0 34 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 7 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _